Platelet Rich Plasma = PRP
PRP stands for Platelet Rich Plasma, or blood plasma with
concentrated platelet content. Platelets are derived from stem cells
in the patient’s bone marrow.
As platelets come into contact with the damaged collagen and
endothelial cells, a fibrin clot forms and growth factors are
recruited and released.
Two growth factors are of particular interest in dealing with
orthopedic injuries. Platelets release transforming growth factor
beta and platelet derived growth factor upon activation at an
injured site. These growth factors and others act synergistically to
enhance access of healthy inflammatory cells to the area of tissue
injury, formation of new blood vessels (angiogenesis), formation of
new connective tissue (fibroplasia) and regeneration of injured
Injection of PRP is a recommended treatment option for both
sub-acute and chronic tendon and ligament injuries. Certain
arthroscopic procedures are also incorporating the use of PRP in
Most equine injection procedures are done under standing sedation
with or without a local nerve block. Sixty milliliters of whole
blood is drawn from the horse in a special syringe, and processed
immediately, to separate the platelet rich fraction. The PRP is then
injected into the injured site and the limb is bandaged for
Re-examination with ultrasonography is conducted every 30-60 days
initially and every 60 to 90 days during the remaining healing
period depending on the degree and location of injury. Horses are
placed on controlled exercise protocol based on the ultrasound
findings and subsequent degree of lameness.
This tip was brought to you by Chuck Maker, DVM (www.alpinehospital.com)
and KAM Animal Services, home of KAM’s “Equine Learning Circle” FREE
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